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Article

The clinical significance of splice variants and subcellular localisation of survivin in non-small cell lung cancers

19 Feb 2008

Abstract excerpt

Survivin is a member of the inhibitor of apoptosis protein family. Survivin has splice variants with different biological functions associated with tumorigenesis. We investigated 134 non-small cell lung cancers (NSCLCs) to study the clinical significance of wild-type survivin, survivin-2B, and survivin-deltaEx3. Real-time PCR analyses were performed for their gene expressions. The subcellular localisation of...

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PMID: 18283319
DOI: 10.1038/sj.bjc.6604253

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