Article
CYP3A5 genotype is associated with elevated blood pressure.
Pharmacogenetics and genomics - 1 Oct 2005
Fromm Martin F, Schmidt Bernhard M W, Pahl Andreas, Jacobi Johannes, Schmieder Roland E
Abstract excerpt
The present study aimed to determine whether a polymorphism in CYP3A5, encoding the major CYP3A enzyme in the human kidney, is associated with blood pressure in Caucasians. A homogenous group of 115 young, white male students with normal or mildly elevated, but untreated blood pressure was included. Blood pressure was recorded by ambulatory 24-h blood pressure-monitoring and compared between individuals with high...
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