Article
CYP3A5 polymorphism, amlodipine and hypertension.
Journal of human hypertension - 1 Mar 2014
Zhang Y-P, Zuo X-C, Huang Z-J, Cai J-J, Wen J, Duan D D, Yuan H
Abstract excerpt
As a major cardiovascular risk factor for stroke, coronary artery disease, heart failure and end-stage renal disease, hypertension affects approximately one billion people and causes large economic burden worldwide. Cytochrome P450 3A5 (CYP3A5), belonging to the CYP3A subfamily, has been implicated in the regulation of blood pressure and may serve as a potential risk factor for the development of hypertension....
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