Article
CYP3A5 polymorphism and sensitivity of blood pressure to dietary salt in Japanese men.
Journal of human hypertension - 1 May 2010
Zhang L, Miyaki K, Wang W, Muramatsu M
Abstract excerpt
The cytochrome P-450 3A5 (CYP3A5) gene has recently been implicated in renal sodium reabsorption and blood pressure regulation. The genetic effect of CYP3A5*1 (expressor) and *3 (reduced-expressor) variants on blood pressure has been studied in African Americans and Caucasians, but not yet in the Asian population. In this cross-sectional study, 238 Japanese male workers were examined to determine whether CYP3A5...
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