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Article

Influence of the CYP3A5 genotype on tacrolimus pharmacokinetics and pharmacodynamics in young kidney transplant recipients.

Pediatric transplantation - 1 May 2007

Ferraresso Mariano, Tirelli Amedea, Ghio Luciana, Grillo Paolo, Martina Valentina, Torresani Erminio, Edefonti Alberto

Abstract excerpt

CYP3A enzyme plays a pivotal role in TAC metabolism. The aim of this study was to analyze retrospectively the influence of CYP3A5 gene polymorphism on TAC pharmacokinetics and pharmacodynamics in 30 teenage kidney transplant recipients. TAC dose, trough blood levels, apparent volume of distributi...

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Source

Identifiers

PMID: 17430486
DOI: 10.1111/j.1399-3046.2006.00662.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17430486-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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