Article
Effect of CYP3A51/3 polymorphism on blood pressure in renal transplant recipients.
Transplantation proceedings - 1 Nov 2012
Torio A, Auyanet I, Montes-Ares O, Guerra R M, Fernandez E J, Perez M A, Ramirez A, Checa M D
Abstract excerpt
BACKGROUND: The cytochrome P450 3A5 (CYP3A5) enzyme has been implicated to determine blood pressure (BP) in humans. Different results have been reported concerning CYP3A5 gene polymorphisms and posttransplantation hypertension in kidney recipients. Our objective was to investigate whether CYP3A5 1/3 polymorphism was associated with ambulatory BP among a population of renal transplant recipients receiving the...
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