Article
Association of Vitamin K epoxide reductase complex 1 (VKORC1) variants with warfarin dose in a Hong Kong Chinese patient population.
Pharmacogenetics and genomics - 1 Oct 2005
Veenstra David L, You Joyce H S, Rieder Mark J, Farin Federico M, Wilkerson Hui-Wen, Blough David K, Cheng Gregory, Rettie Allan E
Abstract excerpt
OBJECTIVE: To evaluate the association of VKORC1 genetic variants with warfarin dose requirements in a Hong Kong Chinese patient population. METHODS: A retrospective study of Hong Kong Chinese patients chronically maintained on warfarin was conducted. Single nucleotide polymorphisms (SNPs) in VKORC1 and CYP2C9 were genotyped. Stable warfarin dose data were retrieved from patient medical records. RESULTS:...
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