Article
Genetic determinants of warfarin dosing in the Han-Chinese population.
Pharmacogenomics - 1 Dec 2009
Lee M T Michael, Chen Chien-Hsiun, Chou Ching-Heng, Lu Liang-Suei, Chuang Hui-Ping, Chen Ying-Ting, Saleem Amir N, Wen Ming-Shien, Chen Jin-Jer, Wu Jer-Yuarn, Chen Yuan-Tsong
Abstract excerpt
UNLABELLED: Warfarin, a widely prescribed oral anticoagulant, is used for the prevention of thromboembolism. Polymorphisms in CYP2C9 and VKORC1 have been shown to be associated with warfarin dose requirements. However, it is likely that other genes could also affect warfarin dose. AIMS: In this study, we aimed to identify additional genes influencing warfarin dosing in the Han-Chinese population. MATERIALS &...
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