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Article

Factors affecting the interindividual variability of warfarin dose requirement in adult Korean patients.

Pharmacogenomics - 1 Apr 2007

Cho Hyun-Jung, Sohn Kie-Ho, Park Hyang-Mi, Lee Kyung-Hoon, Choi BoYoung, Kim Seonwoo, Kim June-Soo, On Young-Keun, Chun Mi-Ryung, Kim Hee-Jin, Kim Jong-Won, Lee Soo-Youn

Abstract excerpt

INTRODUCTION: Warfarin, a commonly prescribed anticoagulant, exhibits large interindividual and interethnic differences in the dose required for its anticoagulation effect. Asian patients require a much lower maintenance dose compared with Caucasians; the explanation for these differences remains unknown. METHODS: We analyzed five single nucleotide polymorphisms of the vitamin K epoxide reductase complex subunit...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17391071
DOI: 10.2217/14622416.8.4.329

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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