Article
Role of transcription factors in motoneuron differentiation of adult human olfactory neuroepithelial-derived progenitors.
Stem cells (Dayton, Ohio) - 1 Feb 2006
Zhang Xiaodong, Cai Jun, Klueber Kathleen M, Guo Zhanfang, Lu Chengliang, Winstead Welby I, Qiu Mengsheng, Roisen Fred J
Abstract excerpt
Neurosphereforming cell (NSFC) lines have been established from cultures of human adult olfactory neuroepithelium. Few of these cells ever express mature neuronal or glial markers in minimal essential medium supplemented with 10% fetal bovine serum or defined medium. However, these neural progenitors have the potential to differentiate along glial or neuronal lineages. To evaluate the potential of NSFCs to form...
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