Article
NG2 and Olig2 expression provides evidence for phenotypic deregulation of cultured central nervous system and peripheral nervous system neural precursor cells.
Stem cells (Dayton, Ohio) - 1 Feb 2007
Dromard Cecile, Bartolami Sylvain, Deleyrolle Loïc, Takebayashi Hirohide, Ripoll Chantal, Simonneau Lionel, Prome Sylvie, Puech Sylvie, Tran Van Ba Christophe, Duperray Christophe, Valmier Jean, Privat Alain, Hugnot Jean-Philippe
Abstract excerpt
Neural stem cells cultured with fibroblast growth factor 2 (FGF2)/epidermal growth factor (EGF) generate clonal expansions called neurospheres (NS), which are widely used for therapy in animal models. However, their cellular composition is still poorly defined. Here, we report that NS derived from several embryonic and adult central nervous system (CNS) regions are composed mainly of remarkable cells coexpressing...
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