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Differentiation of Human Embryonic Stem Cells to Neural Lineages in Adherent Culture by Blocking Bone Morphogenetic Protein Signaling

8 Jul 2005

Abstract excerpt

Human embryonic stem cells (hESCs) have extensive self-renewal capacity and are competent to differentiate into any cell type of the body. They are valuable not only for the study of early human development but also for regenerative medicine. However, how to direct differentiation of hESCs along a particular lineage pathway to a specific cell type remains a challenge. Although hESCs have been shown to...

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PMID: 16002783
DOI: 10.1634/stemcells.2005-0110

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