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Article

Motoneurons derived from embryonic stem cells express transcription factors and develop phenotypes characteristic of medial motor column neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 22 Mar 2006

Soundararajan Prabakaran, Miles Gareth B, Rubin Lee L, Brownstone Robert M, Rafuse Victor F

Abstract excerpt

Embryonic stem (ES) cells differentiate into functional motoneurons when treated with a sonic hedgehog (Shh) agonist and retinoic acid (RA). Whether ES cells can be directed to differentiate into specific subtypes of motoneurons is unknown. We treated embryoid bodies generated from HBG3 ES cells...

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Identifiers

PMID: 16554476
DOI: 10.1523/JNEUROSCI.5537-05.2006
PMCID: PMC6674087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16554476-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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