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Article

Gli2 is a novel regulator of sox2 expression in telencephalic neuroepithelial cells.

Stem cells (Dayton, Ohio) - 1 Jan 2009

Takanaga Hiromi, Tsuchida-Straeten Nobuko, Nishide Kenji, Watanabe Akira, Aburatani Hiroyuki, Kondo Toru

Abstract excerpt

Multipotential neural stem cells (NSCs) in the central nervous system (CNS) proliferate indefinitely and give rise to neurons, astrocytes, and oligodendrocytes. As NSCs hold promise for CNS regeneration, it is important to understand how their proliferation and differentiation are controlled. We show here that the expression of sox2 gene, which is essential for the maintenance of NSCs, is regulated by the Gli2...

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Share to Basic Helix-Loop-Helix Transcription Factors
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Enhancer Elements, Genetic

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Source

Identifiers

PMID: 18927476
DOI: 10.1634/stemcells.2008-0580

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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