Article
Use of duplex PCR-CTPP methods for CYP2E1RsaI/IL-2 T-330G and IL-1B C-31T/TNF-A T-1031C polymorphisms.
Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology - 1 Jan 2005
Atsuta Yoshiko, Kawase Haruya, Hamajima Nobuyuki, Nishio Kazuko, Niwa Yoshimitsu, Tanaka Daisuke, Yamamoto Kazuhito, Tamakoshi Akiko
Abstract excerpt
BACKGROUND: Two duplex polymerase chain reaction (PCR) with confronting two-pair primer (PCR-CTPP) methods were designed for cytochrome P450 (CYP) 2E1 RsaI and interleukin (IL-2) T-330G, and for IL-1B C-31T and tumor necrosis factor-alpha (TNF-A) T-1031C. The four polymorphisms are considered to be functional, and the three cytokines reportedly inhibit CYP2E1 expression. Many studies have reported associations...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.