Article
Significant reduction in breast cancer risk for Japanese women with interleukin 1B -31 CT/TT relative to CC genotype.
Japanese journal of clinical oncology - 1 Oct 2002
Ito Lucy Sayuri, Iwata Hiroji, Hamajima Nobuyuki, Saito Toshiko, Matsuo Keitaro, Mizutani Mitsuhiro, Iwase Takuji, Miura Shigeto, Okuma Katashi, Inoue Manami, Hirose Kaoru, Tajima Kazuo
Abstract excerpt
OBJECTIVE: The present case-control study aimed to examine the associations between breast cancer risk and three functional polymorphisms (Interleukin (IL) -1A C-889T, IL-1B C-31T and IL-1RN 86-bp variable number tandem repeat) related to expression of IL-1beta, which combines estrogen receptor. METHODS: Cases were 231 patients with breast cancer who had been diagnosed 1 month to 6 years before their enrollment...
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