Article
[Genetic polymorphisms of alcohol-metabolizing enzymes and cytokines in patients with alcohol induced pancreatitis and alcoholic liver cirrhosis].
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi - 1 Jun 2004
Kim Myong Sik, Lee Don Haeng, Kang Hyo Seung, Park Hyun Shin, Jung Seok, Lee Jin Woo, Kwon Kye Sook, Kim Pum Soo, Kim Hyung Gil, Shin Yong Woon, Kim Young Soo, Baek Ilhyun, Lee Myung Seok
Abstract excerpt
BACKGROUND/AIMS: Susceptibility to organ damage induced by alcohol may be related to inherited variations (polymorphisms) in alcohol-metabolizing enzymes, or polymorphisms affecting cytokines. The aim of this study was to compare the genotype and allelic frequencies of ADH2, ADH3, ALDH2, cytochrome P450-2E1, IL-1, IL-6, IL-8 and tumor necrosis factor-alpha in patients with alcoholic pancreatitis and alcoholic...
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