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Article

The homologous Drosophila transcriptional adaptors ADA2a and ADA2b are both required for normal development but have different functions.

Molecular and cellular biology - 1 Sept 2005

Pankotai Tibor, Komonyi Orbán, Bodai László, Ujfaludi Zsuzsanna, Muratoglu Selen, Ciurciu Anita, Tora László, Szabad János, Boros Imre

Abstract excerpt

In Drosophila and several other metazoan organisms, there are two genes that encode related but distinct homologs of ADA2-type transcriptional adaptors. Here we describe mutations of the two Ada2 genes of Drosophila melanogaster. By using mutant Drosophila lines, which allow the functional study of individual ADA2s, we demonstrate that both Drosophila Ada2 genes are essential. Ada2a and Ada2b null homozygotes are...

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Identifiers

PMID: 16135810
DOI: 10.1128/MCB.25.18.8215-8227.2005
PMCID: PMC1234310

Genes

ADA2
TAF10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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