Article
dSAP18 and dHDAC1 contribute to the functional regulation of the Drosophila Fab-7 element.
Nucleic acids research - 1 Jan 2005
Canudas Silvia, Pérez Silvia, Fanti Laura, Pimpinelli Sergio, Singh Navjot, Hanes Steven D, Azorín Fernando, Espinás M Lluïsa
Abstract excerpt
It was described earlier that the Drosophila GAGA factor [Trithorax-like (Trl)] interacts with dSAP18, which, in mammals, was reported to be a component of the Sin3-HDAC co-repressor complex. GAGA-dSAP18 interaction was proposed to contribute to the functional regulation of the bithorax complex (BX-C). Here, we show that mutant alleles of Trl, dsap18 and drpd3/hdac1 enhance A6-to-A5 transformation indicating a...
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