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Article

Phenotypical and genetical characterization of the Mad1-2 allele during Drosophila wing development.

Cells & development - 1 Mar 2022

Chen Yao, Liu Tao, Shen Jie, Zhang Junzheng

Abstract excerpt

Growth and patterning of Drosophila wing depends upon the sequential organizing activities of Hedgehog (Hh) and Decapentaplegic (Dpp) signaling pathways. The Hh signaling directly activates the expression of dpp through the transcription factor cubitus interruptus (Ci). Dpp itself functions as a long-range morphogen to promote cell proliferation and differentiation through an essential transcription factor...

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PMID: 34875394
DOI: 10.1016/j.cdev.2021.203761

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