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Article

ARF directly binds DP1: interaction with DP1 coincides with the G1 arrest function of ARF.

Molecular and cellular biology - 1 Sept 2005

Datta Abhishek, Sen Jayita, Hagen Jussara, Korgaonkar Chandrashekhar K, Caffrey Michael, Quelle Dawn E, Hughes Douglas E, Ackerson Timothy J, Costa Robert H, Raychaudhuri Pradip

Abstract excerpt

The tumor suppressor ARF inhibits cell growth in response to oncogenic stress in a p53-dependent manner. Also, there is an increasing appreciation of ARF's ability to inhibit cell growth via multiple p53-independent mechanisms, including its ability to regulate the E2F pathway. We have investigated the interaction between the tumor suppressor ARF and DP1, the DNA binding partner of the E2F family of factors...

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Source

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Identifiers

PMID: 16135794
DOI: 10.1128/MCB.25.18.8024-8036.2005
PMCID: PMC1234342

Genes

E2F1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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ARF directly binds DP1: interaction with DP1 coincides with the G1 arrest function of ARF.PMID 16135794Read ↗

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