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Article

Association of p14ARF with the p120E4FTranscriptional Repressor Enhances Cell Cycle Inhibition

1 Feb 2003

Abstract excerpt

The p14(ARF) tumor suppressor is a key regulator of cellular proliferation and is frequently inactivated in human cancer. This tumor suppressor functions in the p53 and pRb cell cycle regulatory pathways and can effectively activate both pathways to induce growth arrest or cell death. We now report that p14(ARF) forms a complex with the E1A-regulated transcriptional repressor, p120(E4F). p120(E4F) contacts...

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Identifiers

PMID: 12446718
DOI: 10.1074/jbc.m210978200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of p14ARF with the p120E4FTranscriptional Repressor Enhances Cell Cycle InhibitionPMID 12446718Read ↗

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