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Article

Detection of DNA copy number alterations using penalized least squares regression.

Bioinformatics (Oxford, England) - 15 Oct 2005

Huang Tao, Wu Baolin, Lizardi Paul, Zhao Hongyu

Abstract excerpt

MOTIVATION: Genomic DNA copy number alterations are characteristic of many human diseases including cancer. Various techniques and platforms have been proposed to allow researchers to partition the whole genome into segments where copy numbers change between contiguous segments, and subsequently to quantify DNA copy number alterations. In this paper, we incorporate the spatial dependence of DNA copy number data...

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PMID: 16131523
DOI: 10.1093/bioinformatics/bti646

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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