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Article

A flexible rank-based framework for detecting copy number aberrations from array data.

Bioinformatics (Oxford, England) - 15 Mar 2009

LaFramboise Thomas, Winckler Wendy, Thomas Roman K

Abstract excerpt

MOTIVATION: DNA copy number aberration--both inherited and sporadic--is a significant contributor to a variety of human diseases. Copy number characterization is therefore an area of intense research. Probe hybridization-based arrays are important tools used to measure copy number in a high-throughput manner. RESULTS: In this article, we present a simple but powerful nonparametric rank-based approach to detect...

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Identifiers

PMID: 19176555
DOI: 10.1093/bioinformatics/btp063
PMCID: PMC2732300

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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