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Article

Knockdown of type 3 iodothyronine deiodinase severely perturbs both embryonic and early larval development in zebrafish.

Endocrinology - 1 Apr 2014

Heijlen Marjolein, Houbrechts Anne M, Bagci Enise, Van Herck Stijn L J, Kersseboom Simone, Esguerra Camila V, Blust Ronny, Visser Theo J, Knapen Dries, Darras Veerle M

Abstract excerpt

Exposure to appropriate levels of thyroid hormones (THs) at the right time is of key importance for normal development in all vertebrates. Type 3 iodothyronine deiodinase (D3) is the prime TH-inactivating enzyme, and its expression is highest in the early stages of vertebrate development, implying that it may be necessary to shield developing tissues from overexposure to THs. We used antisense morpholino...

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Share to Embryo, Nonmammalian
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Intestines

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Share to Oligonucleotides, Antisense

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Identifiers

PMID: 24467742
DOI: 10.1210/en.2013-1660

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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