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Article

Association of polymorphisms in NOS3 with the ankle-brachial index in hypertensive adults.

Atherosclerosis - 1 Feb 2008

Kullo Iftikhar J, Greene M Todd, Boerwinkle Eric, Chu Jian, Turner Stephen T, Kardia Sharon L R

Abstract excerpt

We investigated the association of 14 polymorphisms in the endothelial nitric oxide synthase gene (NOS3) with ankle brachial index (ABI) in non-Hispanic white hypertensives belonging to hypertensive sibships. Subjects (n=659, mean age 61+/-9 years, 54% women) underwent measurement of ABI using a standard protocol, and the lowest of 4 ABI values was used in the analyses. Non-synonymous SNPs with a minor allele...

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Source

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Identifiers

PMID: 17367796
DOI: 10.1016/j.atherosclerosis.2007.02.008
PMCID: PMC2858046

Genes

NOS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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