Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reduced appetite for caffeine in adenosine A(2A) receptor knockout mice.

European journal of pharmacology - 20 Sept 2005

El Yacoubi Malika, Ledent Catherine, Parmentier Marc, Costentin Jean, Vaugeois Jean-Marie

Abstract excerpt

Adenosine A(2A) receptor knockout mice (A(2A)R KO) were compared to wild-type controls (A(2A)R WT) in a caffeine intake paradigm. When mice had ad libitum access to caffeine (0.3 g/l) and water in a two-bottle paradigm for 12 consecutive days, adenosine A(2A)R KO mice drank less caffeinated solution, demonstrating a reduced appetite for caffeine as compared to adenosine A(2A)R WT mice. These data reveal an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Appetite
Share to Caffeine
Share to Drinking

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Mice, Knockout

Share to Receptor, Adenosine A2A

Source

Identifiers

PMID: 16129427
DOI: 10.1016/j.ejphar.2005.07.022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reduced appetite for caffeine in adenosine A(2A) receptor knockout mice.PMID 16129427Read ↗

Mice heterozygous for both A1 and A(2A) adenosine receptor genes show similarities to mice given long-term caffeine.Semantic proximity Read ↗

A1 receptor deficiency causes increased insulin and glucagon secretion in mice.Semantic proximity Read ↗

Involvement of A2A receptors in anxiolytic, locomotor and motivational properties of ethanol in mice.Semantic proximity Read ↗

Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens.Semantic proximity Read ↗

A genetic variation in the adenosine A2A receptor gene (ADORA2A) contributes to individual sensitivity to caffeine effects on sleep.Semantic proximity Read ↗

Sex differences in mouse heart rate and body temperature and in their regulation by adenosine A1 receptors.Semantic proximity Read ↗

Adenosine receptor blockade reverses hypophagia and enhances locomotor activity of dopamine-deficient mice.Semantic proximity Read ↗

Alcohol drinking in MCH receptor-1-deficient mice.Semantic proximity Read ↗

Selective attenuation of psychostimulant-induced behavioral responses in mice lacking A(2A) adenosine receptors.Semantic proximity Read ↗

Characterisation of central adenosine A(1) receptors and adenosine transporters in mice lacking the adenosine A(2a) receptor.Semantic proximity Read ↗

Coffee effectively attenuates impaired attention in ADORA2A C/C-allele carriers during chronic sleep restriction.Semantic proximity Read ↗

Enhanced neurodegeneration after a high dose of methamphetamine in adenosine A3 receptor null mutant mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.