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Article

Adenosine receptor blockade reverses hypophagia and enhances locomotor activity of dopamine-deficient mice.

Proceedings of the National Academy of Sciences of the United States of America - 4 Feb 2003

Kim Douglas S, Palmiter Richard D

Abstract excerpt

Adenosine receptors modulate dopaminergic function by regulating dopamine release in presynaptic neurons and intracellular signaling in postsynaptic striatal neurons. To investigate how adenosine impinges on the action of dopamine in feeding and locomotion, genetically altered, dopamine-deficient mice were treated with adenosine receptor antagonists. Acute administration of the nonselective adenosine receptor...

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Identifiers

PMID: 12538862
DOI: 10.1073/pnas.252753799
PMCID: PMC298775

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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