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Article

A1 receptor deficiency causes increased insulin and glucagon secretion in mice.

Biochemical pharmacology - 3 Dec 2007

Johansson Stina M, Salehi Albert, Sandström Marie E, Westerblad Håkan, Lundquist Ingmar, Carlsson Per-Ola, Fredholm Bertil B, Katz Abram

Abstract excerpt

Adenosine influences metabolism and the adenosine receptor antagonist caffeine decreases the risk of type 2 diabetes. In this study the metabolic role of one adenosine receptor subtype, the adenosine A(1)R, was evaluated in mice lacking this receptor [A(1)R (-/-)]. The HbA1c levels and body weigh...

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Source

Identifiers

PMID: 17869224
DOI: 10.1016/j.bcp.2007.08.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17869224-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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