Article
Validation of the association between the gene encoding 5-lipoxygenase-activating protein and myocardial infarction in a Japanese population.
Circulation journal : official journal of the Japanese Circulation Society - 1 Sept 2005
Kajimoto Kazuaki, Shioji Keisuke, Ishida Chisaki, Iwanaga Yoshitaka, Kokubo Yoshihiro, Tomoike Hitonobu, Miyazaki Shun-ichi, Nonogi Hiroshi, Goto Yoichi, Iwai Naoharu
Abstract excerpt
BACKGROUND: Recently, the 5-lipoxygenase activating protein gene (ALOX5AP) was reported to confer a risk of myocardial infarction (MI) and stroke, independent of conventional risk factors. The purpose of the present study was to validate those findings in a Japanese population. METHODS AND RESULTS: The study population consisted of 1,875 subjects (males 871, females 1,004) recruited from the Suita study (control...
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