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A tagging SNP in ALOX5AP and risk of stroke: a haplotype-based analysis among eastern Chinese Han population.

Molecular biology reports - 1 Oct 2011

Sun Hao, Wu Hao, Zhang Jing, Wang Jun, Lu Ying, Ding Haixia, Xiao Hang, Zhang Jinsong

Abstract excerpt

A genome-wide approach found significant association of two at-risk haplotypes (HapA, HapB) in the ALOX5AP gene with myocardial infarction and stroke. To date, it is still controversial whether ALOX5AP gene polymorphisms are risk factors for stroke. The aim of the present study is to investigate the association between the ALOX5AP gene polymorphism and the risk for stroke in Eastern Chinese Han population with a...

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PMID: 21153769
DOI: 10.1007/s11033-010-0610-4

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