Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Variants in the Transcriptional Regulatory Region of the ALOX5AP gene and Susceptibility to Ischemic Stroke in Chinese Populations.

Scientific reports - 15 Jul 2016

Yang Dongzhi, Huang Xiangnan, Cui Chuanju, Zhang Yuchao, Li Ya, Zang Xin, He Ying, Zheng Hong

Abstract excerpt

No coding sequence variants of the ALOX5AP gene that lead to amino acid substitutions have been identified. A two-stage study design was used to explore the relationship between variants in the transcriptional regulatory region of ALOX5AP gene and ischemic stroke (IS) risk in Chinese populations. IS was determined using CT and/or MRI. First, 18 SNPs, located in the upstream promoter region of ALOX5AP gene, were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5-Lipoxygenase-Activating Proteins
Share to China

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Regulatory Networks

Share to Ischemia

Share to Linkage Disequilibrium

Share to Promoter Regions, Genetic

Share to Stroke

Share to Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 27416969
DOI: 10.1038/srep29513
PMCID: PMC4945871

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Variants in the Transcriptional Regulatory Region of the ALOX5AP gene and Susceptibility to Ischemic Stroke in Chinese Populations.PMID 27416969Read ↗

A promoter polymorphism (rs17222919, -1316T/G) of ALOX5AP gene is associated with decreased risk of ischemic stroke in two independent Chinese populations.Semantic proximity Read ↗

A tagging SNP in ALOX5AP and risk of stroke: a haplotype-based analysis among eastern Chinese Han population.Semantic proximity Read ↗

Genetic variants in the promoter region of the ALOX5AP gene and susceptibility of ischemic stroke.Semantic proximity Read ↗

A novel risk haplotype of ALOX5AP gene is associated with ischemic stroke in Chinese Han population.Semantic proximity Read ↗

Allele-specific methylation contributed by CpG-SNP is associated with regulation of ALOX5AP gene expression in ischemic stroke.Semantic proximity Read ↗

Correlation between cerebral infarction and ALOX5AP gene expression.Semantic proximity Read ↗

ALOX5AP genetic variants and risk of atherothrombotic stroke in the Taiwanese population.Semantic proximity Read ↗

A Promoter polymorphism (rs17222919, -1316T/G) of ALOX5AP is associated with intracerebral hemorrhage in Korean population.Semantic proximity Read ↗

ALOX5AP rs10507391 polymorphism and the risk of ischemic stroke in Caucasians: an update meta-analysis.Semantic proximity Read ↗

Arachidonate 5-lipoxygenase-activating protein (ALOX5AP) gene rs4073259 polymorphism not associated with ischemic stroke in the northeastern Chinese Han population.Semantic proximity Read ↗

Association of ALOX5AP gene single nucleotide polymorphisms and cerebral infarction in the Han population of northern China.Semantic proximity Read ↗

Association of ALOX5AP rs10507391/SG13S114 A>T polymorphism with cerebral infarction in the Chinese population: a meta-analysis study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.