Article
ALOX5AP genetic variants and risk of atherothrombotic stroke in the Taiwanese population.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Dec 2011
Lee Jiann-Der, Lee Tsong-Hai, Huang Yen-Chu, Chang Yeu-Jhy, Chang Chien-Hung, Hsu Huan-Lin, Lin Ya-Hui, Wu Chih-Ying, Lee Meng, Huang Ying-Chih, Ryu Shan-Jin, Hsiao Kuang-Ming
Abstract excerpt
We explored the role of variants of the arachidonate 5-lipoxygenase-activating protein (ALOX5AP) gene as factors for atherothrombotic stroke (ATS). A HapMap-based haplotype-tagging single nucleotide polymorphism (htSNP) association study was conducted in an isolated Taiwanese population. Multivariate logistic regression analyses revealed that patients with the GG/CG genotype of rs4293222 and the AA/AG genotype of...
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