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Article

A promoter polymorphism (rs17222919, -1316T/G) of ALOX5AP gene is associated with decreased risk of ischemic stroke in two independent Chinese populations.

PloS one - 1 Jan 2015

Fan Yujia, Chen Hui, Li Aifan, Shi Yunshu, Zhang Yuchao, Feng Qingchuan, Sun Yan, Zheng Hong, He Ying

Abstract excerpt

No coding sequence variants of the gene encoding 5-lipoxygenase-activating protein (ALOX5AP) leading to amino acid substitutions have been identified. Therefore, variants in the ALOX5AP promoter region have received attention recently. The purpose of this study was to explore whether the promoter...

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Identifiers

PMID: 25815512
DOI: 10.1371/journal.pone.0122393
PMCID: PMC4376390

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25815512-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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