Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clock gene polymorphisms and narcolepsy in positive and negative HLA-DQB1*0602 patients.

Brain research. Molecular brain research - 31 Oct 2005

Moreira Fabio, Pedrazzoli Mario, Dos Santos Coelho Fernando Morgadinho, Pradella-Hallinan Marcia, Lopes da Conceição Maria Cecília, Pereira Peregrino Alberto Jorge, de Oliveira Emílio Carlos, Tufik Sergio

Abstract excerpt

Narcolepsy is a chronic sleep disorder. It is linked to the HLA-DQB1*0602 allele. A recent report established a genetic linkage between narcolepsy and the chromosomal region 4p13-q21 that contains the Clock gene. We studied two SNPs in the Clock gene aiming to find any association with narcolepsy. We did not find differences in genetic frequencies in the patients group. We concluded that these two SNPs are not...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CLOCK Proteins
Share to DNA Primers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HLA-DQ Antigens

Share to HLA-DQ beta-Chains

Share to Membrane Glycoproteins

Share to Narcolepsy

Share to Polymerase Chain Reaction

Share to Trans-Activators

Source

Identifiers

PMID: 16125818
DOI: 10.1016/j.molbrainres.2005.07.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clock gene polymorphisms and narcolepsy in positive and negative HLA-DQB1*0602 patients.PMID 16125818Read ↗

New susceptibility variants to narcolepsy identified in HLA class II region.Semantic proximity Read ↗

Negative association of the HLA-DRB1*1502-DQB1*0601 haplotype with human narcolepsy.Semantic proximity Read ↗

HLA class II haplotype and sequence analysis support a role for DQ in narcolepsy.Semantic proximity Read ↗

Homozygous HLA-DQB1*06:02 combined with T-cell receptor alpha polymorphism results in narcolepsy onset - A familial case report.Semantic proximity Read ↗

Association Study of HLA-DQB1*0602 Allele in Iranian Patients with Narcolepsy.Semantic proximity Read ↗

Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy.Semantic proximity Read ↗

Association between human leukocyte antigen class II-DR-DQ and narcolepsy: a case control study.Semantic proximity Read ↗

HLA-DQA, -DQB and -DRB allele contribution to narcolepsy susceptibility.Semantic proximity Read ↗

Identification of the variations in the CPT1B and CHKB genes along with the HLA-DQB1*06:02 allele in Turkish narcolepsy patients and healthy persons.Semantic proximity Read ↗

Prevalence of the HLA-DQB1*0602 allele in narcolepsy and idiopathic hypersomnia patients seen at a sleep disorders outpatient unit in São Paulo.Semantic proximity Read ↗

Prevalence of HLA DQB1*0602 allele in patients with migraine.Semantic proximity Read ↗

DQB1*0301 and DQB1*0601 modulate narcolepsy susceptibility in Koreans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.