Article
Prevalence of HLA DQB1*0602 allele in patients with migraine.
Arquivos de neuro-psiquiatria - 1 Dec 2007
Coelho Fernando Morgadinho Santos, Pradella-Hallinan Márcia, Abud Paulo Corrêa, Predazzoli Neto Mario, Moreira Fabio, Bittencourt Lia Rita Azeredo, Peres Mario Fernandes Pietro, Tufik Sérgio
Abstract excerpt
BACKGROUND: Studies have shown a high prevalence of migraine among narcoleptic patients. HLA-DQB1*0602 and HLA DRB1 alleles are closely associated with narcolepsy. An increase in the HLA-DRB1 allele frequency in patients with visual aura has raised greater awareness of the genetic background in migraine. PURPOSE: Since the regions DR and DQ of the HLA are in tightly linkage desiquilibrium we hypothesize that...
Topics
- Adult
- Alleles
- Case-Control Studies
- Female
- Genetic Markers
- Genetic Predisposition to Disease
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- Humans
- Male
- Membrane Glycoproteins
- Migraine with Aura
- Migraine without Aura
- Polymerase Chain Reaction
- Prevalence