Article
Prevalence of HLA DQB1*0602 allele in patients with migraine.
Arquivos de neuro-psiquiatria - 1 Dec 2007
Coelho Fernando Morgadinho Santos, Pradella-Hallinan Márcia, Abud Paulo Corrêa, Predazzoli Neto Mario, Moreira Fabio, Bittencourt Lia Rita Azeredo, Peres Mario Fernandes Pietro, Tufik Sérgio
Abstract excerpt
BACKGROUND: Studies have shown a high prevalence of migraine among narcoleptic patients. HLA-DQB1*0602 and HLA DRB1 alleles are closely associated with narcolepsy. An increase in the HLA-DRB1 allele frequency in patients with visual aura has raised greater awareness of the genetic background in migraine. PURPOSE: Since the regions DR and DQ of the HLA are in tightly linkage desiquilibrium we hypothesize that...
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