Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Amyloid precursor protein interacts with notch receptors

1 Jan 2005

Abstract excerpt

The amyloid precursor protein (APP) must fulfill important roles based on its sequence conservation from fly to human. Although multiple functions for APP have been proposed, the best-known role for this protein is as the precursor of Abeta peptide, a neurotoxic 39-43-amino acid peptide crucial to the pathogenesis of Alzheimer's disease. To investigate additional roles for APP with an eye toward understanding the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Epigenetics and DNA Methylation
Share to Genetics and Neurodevelopmental Disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16118793
DOI: 10.1002/jnr.20625

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Amyloid precursor protein interacts with notch receptorsPMID 16118793Read ↗

BRI2 interacts with amyloid precursor protein (APP) and regulates amyloid beta (Abeta) production.Semantic proximity Read ↗

Notch 1 interacts with the amyloid precursor protein in a Numb-independent manner.Semantic proximity Read ↗

Cellular functions of the amyloid precursor protein from development to dementia.Semantic proximity Read ↗

Yeast Two-Hybrid Screening for Proteins that Interact with the Extracellular Domain of Amyloid Precursor Protein.Semantic proximity Read ↗

Identification of NEEP21 as a β-Amyloid Precursor Protein-Interacting Protein<i>In Vivo</i>That Modulates Amyloidogenic Processing<i>In Vitro</i>Semantic proximity Read ↗

The interactome of the amyloid β precursor protein family members is shaped by phosphorylation of their intracellular domainsSemantic proximity Read ↗

Amyloid Precursor Protein (APP) Regulates Gliogenesis and Neurogenesis of Human Neural Stem Cells by Several Signaling PathwaysSemantic proximity Read ↗

Interaction between amyloid precursor protein and presenilins in mammalian cells: Implications for the pathogenesis of Alzheimer diseaseSemantic proximity Read ↗

The APP Intracellular Domain Is Required for Normal Synaptic Morphology, Synaptic Plasticity, and Hippocampus-Dependent Behavior.Semantic proximity Read ↗

NMDA receptor/amyloid precursor protein interactions: a comparison between wild-type and amyloid precursor protein mutations associated with familial Alzheimer's disease.Semantic proximity Read ↗

The phosphoS655 Alzheimer’s Amyloid Precursor Protein (APP) interactome in neuronal differentiationSemantic proximity Read ↗

Presenilin-interacting proteinsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.