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Article

Polymorphisms in the estrogen receptor beta (ESR2) gene are associated with bone mineral density in Caucasian men and women.

The Journal of clinical endocrinology and metabolism - 1 Nov 2005

Ichikawa Shoji, Koller Daniel L, Peacock Munro, Johnson Michelle L, Lai Dongbing, Hui Siu L, Johnston C Conrad, Foroud Tatiana M, Econs Michael J

Abstract excerpt

CONTEXT: A major determinant of osteoporotic fractures is peak bone mineral density (BMD), which is a highly heritable trait. Recently, we identified significant linkage for hip BMD in premenopausal sister pairs at chromosome 14q (LOD score = 3.5), where the estrogen receptor beta gene (ESR2) is located. OBJECTIVE: The objective of the study was to determine whether ESR2 polymorphisms are associated with normal...

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Share to Bone Density
Share to Chromosomes, Human, Pair 14

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Estrogen Receptor beta

Share to ESR2 gene

Share to Linkage Disequilibrium

Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait Loci

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Source

Open in PubMed Open full text

Identifiers

PMID: 16118344
DOI: 10.1210/jc.2004-2253
PMCID: PMC1948071

Genes

ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymorphisms in the estrogen receptor beta (ESR2) gene are associated with bone mineral density in Caucasian men and women.PMID 16118344Read ↗

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