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Article

GREB1 genetic variants are associated with bone mineral density in Caucasians.

Journal of bone and mineral metabolism - 1 Mar 2018

Hegarty Kevin G, Drummond Frances J, Daly Mary, Shanahan Fergus, Molloy Michael G

Abstract excerpt

Gaining an understanding of factors contributing to bone quality is key to the development of effective preventative treatments for osteoporosis and reduction in osteoporotic fractures. Oestrogen is a strong regulator of bone remodelling which maintains skeletal structural integrity. The growth regulation by oestrogen in breast cancer 1 (GREB1) gene, with an as yet undefined function, is an early response gene in...

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PMID: 28293781
DOI: 10.1007/s00774-017-0823-x

Genes

GREB1

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