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Article

Bone mineral density is associated with vitamin D related rs6013897 and estrogen receptor polymorphism rs4870044: The Tromsø study.

PloS one - 1 Jan 2017

Martinaityte Ieva, Jorde Rolf, Emaus Nina, Eggen Anne Elise, Joakimsen Ragnar Martin, Kamycheva Elena

Abstract excerpt

BACKGROUND: Bone mineral density (BMD) is determined by bone remodeling processes regulated by endocrine, autocrine and genetic mechanisms. Thus, some studies have reported that BMD is associated with single nucleotide polymorphisms (SNPs) associated with vitamin D receptor (VDR), serum 25(OH)D levels and estrogen receptor 1 (ESR1), but without consensus. Therefore, we aimed to map and compare the risk genotypes...

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Source

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Identifiers

PMID: 28253304
DOI: 10.1371/journal.pone.0173045
PMCID: PMC5333870

Genes

ESR1
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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