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Article

Association with replication between estrogen-related receptor gamma (ESRRgamma) polymorphisms and bone phenotypes in women of European ancestry.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Apr 2010

Elfassihi Latifa, Giroux Sylvie, Bureau Alexandre, Laflamme Nathalie, Cole David Ec, Rousseau François

Abstract excerpt

Osteoporosis is a bone disease characterized by low bone mineral density (BMD), a highly heritable polygenic trait. Women are more prone than men to develop osteoporosis owing to a lower peak bone mass and accelerated bone loss at menopause. Lack of estrogen thus is a major risk factor for osteoporosis. In addition to having strong similarity to the estrogen receptor 1 (ESR1), the orphan nuclear estrogen-related...

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Identifiers

PMID: 19821770
DOI: 10.1359/jbmr.091014

Genes

ESR1

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