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Article

Brucella abortus virB12 is expressed during infection but is not an essential component of the type IV secretion system.

Infection and immunity - 1 Sept 2005

Sun Yao-Hui, Rolán Hortensia G, den Hartigh Andreas B, Sondervan David, Tsolis Renée M

Abstract excerpt

The Brucella abortus virB operon, consisting of 11 genes, virB1 to virB11, and two putative genes, orf12 (virB12) and orf13, encodes a type IV secretion system (T4SS) that is required for intracellular replication and persistent infection in the mouse model. This study was undertaken to determine whether orf12 (virB12) encodes an essential part of the T4SS apparatus. The virB12 gene was found to encode a 17-kDa...

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Identifiers

PMID: 16113325
DOI: 10.1128/IAI.73.9.6048-6054.2005
PMCID: PMC1231059

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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