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Comparative proteome analysis of Brucella abortus 2308 and its virB type IV secretion system mutant reveals new T4SS-related candidate proteins.

Journal of proteomics - 18 Nov 2011

Paredes-Cervantes Vladimir, Flores-Mejía Raúl, Moreno-Lafont Martha C, Lanz-Mendoza Humberto, Tello-López Ángel T, Castillo-Vera Jane, Pando-Robles Victoria, Hurtado-Sil Gerardo, González-González Edith, Rodríguez-Cortés Octavio, Gutiérrez-Hoya Adriana, Vega-Ramírez María T, López-Santiago Rubén

Abstract excerpt

Brucella abortus is an alpha-2 proteobacteria with a type IV secretion system (T4SS) known as virB, which is necessary to gain virulence by building up a replicative vacuole associated with the endoplasmic reticulum of the host cell. A virB T4SS mutant of the B. abortus 2308 strain and its wild-type strain were grown in acid medium in order to obtain and analyze their proteomes, looking for putative proteins that...

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PMID: 21875698
DOI: 10.1016/j.jprot.2011.07.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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