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Article

Dimerization and interactions of Brucella suis VirB8 with VirB4 and VirB10 are required for its biological activity.

Proceedings of the National Academy of Sciences of the United States of America - 9 May 2006

Paschos Athanasios, Patey Gilles, Sivanesan Durga, Gao Chan, Bayliss Richard, Waksman Gabriel, O'callaghan David, Baron Christian

Abstract excerpt

VirB8-like proteins are essential components of type IV secretion systems, bacterial virulence factors that mediate the translocation of effector molecules from many bacterial pathogens into eukaryotic cells. Based on cell biological, genetic, and x-ray crystallographic data, VirB8 was proposed to undergo multiple protein-protein interactions to mediate assembly of the translocation machinery. Here we report the...

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Identifiers

PMID: 16648257
DOI: 10.1073/pnas.0600862103
PMCID: PMC1464329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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