Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RNA interference is an antiviral defence mechanism in Caenorhabditis elegans.

Nature - 18 Aug 2005

Wilkins Courtney, Dishongh Ryan, Moore Steve C, Whitt Michael A, Chow Marie, Machaca Khaled

Abstract excerpt

RNA interference (RNAi) is an evolutionarily conserved sequence-specific post-transcriptional gene silencing mechanism that is well defined genetically in Caenorhabditis elegans. RNAi has been postulated to function as an adaptive antiviral immune mechanism in the worm, but there is no experimental evidence for this. Part of the limitation is that there are no known natural viral pathogens of C. elegans. Here we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Models, Animal

Share to RNA-Binding Proteins

Share to RNA Interference

Share to RNA, Small Interfering

Share to Substrate Specificity

Share to Vesicular stomatitis Indiana virus

Source

Identifiers

PMID: 16107852
DOI: 10.1038/nature03957

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RNA interference is an antiviral defence mechanism in Caenorhabditis elegans.PMID 16107852Read ↗

An antiviral role for the RNA interference machinery in Caenorhabditis elegans.Semantic proximity Read ↗

Shared and unique mechanisms of RNAi-mediated antiviral immunity in C. elegansSemantic proximity Read ↗

An RIG-I-Like RNA helicase mediates antiviral RNAi downstream of viral siRNA biogenesis in Caenorhabditis elegans.Semantic proximity Read ↗

Collagen and actin network mediate antiviral immunity against Orsay in C. elegans intestinal cellsSemantic proximity Read ↗

Natural and experimental infection of Caenorhabditis nematodes by novel viruses related to nodaviruses.Semantic proximity Read ↗

An Alternative STAT Signaling Pathway Acts in Viral Immunity in Caenorhabditis elegans.Semantic proximity Read ↗

Characterizing the role of RSD-6 in the biogenesis of virus-derived small interfering RNAs and the modulation of viral pathogenesis.Semantic proximity Read ↗

Characterizing the role of RSD-6 in the biogenesis of virus-derived small interfering RNAs and the modulation of viral pathogenesisSemantic proximity Read ↗

An SRR1 domain-containing protein is required for efficient Orsay virus replication in Caenorhabditis elegans.Semantic proximity Read ↗

The alg-1 Gene Is Necessary for Orsay Virus Replication in Caenorhabditis elegans.Semantic proximity Read ↗

RNAi-mediated immunity provides strong protection against the negative-strand RNA vesicular stomatitis virus in <i>Drosophila</i>Semantic proximity Read ↗

Homologous RIG-I–like helicase proteins direct RNAi-mediated antiviral immunity in <i>C. elegans</i> by distinct mechanismsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.