Article
The Arabidopsis Pot1 and Pot2 proteins function in telomere length homeostasis and chromosome end protection.
Molecular and cellular biology - 1 Sept 2005
Shakirov Eugene V, Surovtseva Yulia V, Osbun Nathan, Shippen Dorothy E
Abstract excerpt
Pot1 (protection of telomeres 1) is a single-stranded telomere binding protein that is essential for chromosome end protection and telomere length homeostasis. Arabidopsis encodes two Pot1-like proteins, dubbed AtPot1 and AtPot2. Here we show that telomeres in transgenic plants expressing a truncated AtPot1 allele lacking the N-terminal oligonucleotide/oligosaccharide binding fold (P1DeltaN) are 1 to 1.5 kb...
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