Article
Arabidopsis POT1 associates with the telomerase RNP and is required for telomere maintenance.
The EMBO journal - 8 Aug 2007
Surovtseva Yulia V, Shakirov Eugene V, Vespa Laurent, Osbun Nathan, Song Xiangyu, Shippen Dorothy E
Abstract excerpt
POT1 is a single-copy gene in yeast and humans that encodes a single-strand telomere binding protein required for chromosome end protection and telomere length regulation. In contrast, Arabidopsis harbors multiple, divergent POT-like genes that bear signature N-terminal OB-fold motifs, but otherwise share limited sequence similarity. Here, we report that plants null for AtPOT1 show no telomere deprotection...
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