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Article

STN1 protects chromosome ends in Arabidopsis thaliana.

Proceedings of the National Academy of Sciences of the United States of America - 16 Dec 2008

Song Xiangyu, Leehy Katherine, Warrington Ross T, Lamb Jonathan C, Surovtseva Yulia V, Shippen Dorothy E

Abstract excerpt

Telomeres shield the natural ends of chromosomes from nucleolytic attack, recognition as double-strand breaks, and inappropriate processing by DNA repair machinery. The trimeric Stn1/Ten1/Cdc13 complex is critical for chromosome end protection in Saccharomyces cerevisiae, while vertebrate telomeres are protected by shelterin, a complex of six proteins that does not include STN1 or TEN1. Recent studies demonstrate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19064932
DOI: 10.1073/pnas.0807867105
PMCID: PMC2604966

Genes

STN1
TEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

STN1 protects chromosome ends in Arabidopsis thaliana.PMID 19064932Read ↗

Conserved telomere maintenance component 1 interacts with STN1 and maintains chromosome ends in higher eukaryotes.Semantic proximity Read ↗

Protection of telomeres by a conserved Stn1–Ten1 complexSemantic proximity Read ↗

MERISTEM DISORGANIZATION1 encodes TEN1, an essential telomere protein that modulates telomerase processivity in Arabidopsis.Semantic proximity Read ↗

The Arabidopsis Pot1 and Pot2 proteins function in telomere length homeostasis and chromosome end protection.Semantic proximity Read ↗

OB Fold-containing Protein 1 (OBFC1), a Human Homolog of Yeast Stn1, Associates with TPP1 and Is Implicated in Telomere Length RegulationSemantic proximity Read ↗

Evolution of CST function in telomere maintenanceSemantic proximity Read ↗

Tying up the Ends: Plasticity in the Recognition of Single-Stranded DNA at TelomeresSemantic proximity Read ↗

Role of STN1 and DNA polymerase α in telomere stability and genome-wide replication in Arabidopsis.Semantic proximity Read ↗

Structure of the Human Telomeric Stn1-Ten1 Capping ComplexSemantic proximity Read ↗

TEN1 is essential for CDC13-mediated telomere capping.Semantic proximity Read ↗

DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA.Semantic proximity Read ↗

ATR cooperates with CTC1 and STN1 to maintain telomeres and genome integrity in Arabidopsis.Semantic proximity Read ↗

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