Article
An evaluation of the performance of tag SNPs derived from HapMap in a Caucasian population.
PLoS genetics - 1 Mar 2006
Montpetit Alexandre, Nelis Mari, Laflamme Philippe, Magi Reedik, Ke Xiayi, Remm Maido, Cardon Lon, Hudson Thomas J, Metspalu Andres
Abstract excerpt
The Haplotype Map (HapMap) project recently generated genotype data for more than 1 million single-nucleotide polymorphisms (SNPs) in four population samples. The main application of the data is in the selection of tag single-nucleotide polymorphisms (tSNPs) to use in association studies. The usefulness of this selection process needs to be verified in populations outside those used for the HapMap project. In...
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