Clinical significance of the genotype and core promoter/pre-core mutations in hepatitis B virus carriers.

doi:10.1159/000090789

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Article

Clinical significance of the genotype and core promoter/pre-core mutations in hepatitis B virus carriers.

Intervirology - 1 Jan 2006

Hagiwara Satoru, Kudo Masatoshi, Minami Yasunori, Chung Hobyung, Nakatani Tatsuya, Fukunaga Toyokazu, Osaki Yukio, Yamashita Yukitaka, Kajimura Kozo

Abstract excerpt

It has been shown that clinical and virological characteristics vary among hepatitis B virus (HBV) genotypes. In this study, we measured the virus level, disease severity, and presence or absence of core promoter (CP)/pre-core (PC) mutations in 241 HBV carriers, and investigated the clinical significance of measuring the HBV genotype. In genotype C HBV carriers, the proportion of hepatitis B e antigen...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Carrier State
Female
Genotype
Hepatitis B
Hepatitis B Antigens
Hepatitis B Core Antigens
Hepatitis B virus
Humans
Male
Middle Aged
Point Mutation
Promoter Regions, Genetic

Source

Open in PubMed

Identifiers

PMID: 16407657
DOI: 10.1159/000090789

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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